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. Author manuscript; available in PMC: 2022 Nov 18.
Published in final edited form as: Nat Med. 2020 Aug 10;26(9):1468–1479. doi: 10.1038/s41591-020-1006-1

Extended Data Figure 8. Comparison of CD3− populations in patients with relapsed/refractory cHL split by best overall response at baseline (CR, PR, PD).

Extended Data Figure 8.

To quantify differences between these groups (CR n=12, PR n=15, PD n=8), we determined the number of cells that each sample contributed to a given cluster and applied Cuzick trend test (two-sided nominal p-values) with Benjamini-Hochberg (BH) corrections for p ≤ 0.05 (B cells and NK cells separately). Shown here graphically are box plots (generated in GraphPad Prism) defining the 25th and 75th percentile and median values and whiskers for minimum and maximum values: a) Monocyte clusters; b) B-cell clusters [(2) CXCR5+ CD73−IRF4−, (3) CXCR5+ CD73+ IRF4+]; c) Neutrophils; d) NK-cell clusters and e) CD68+CD4+GrB+ cells.