. 2022 Nov 13;58:102540. doi: 10.1016/j.redox.2022.102540

Table 2.

Effects of HTL on cognitive functions and MCA flow velocity in WT and iNOS^−/− mice.

Groups	WT (Control)	iNOS^−/−	WT + HTL	iNOS^−/−+ HTL
Swimming distance in quadrant (m)	2.69 ± 0.31	2.57 ± 0.39	1.27 ± 0.33^a	2.47 ± 0.35^b
Swimming distance out of quadrant (m)	3.49 ± 0.58	3.81 ± 0.52	4.85 ± 0.47^a	3.53 ± 0.46^b
Total swimming distance (m)	6.13 ± 0.78	6.49 ± 0.91	6.09 ± 0.62	6.17 ± 0.83
Swimming distance in quadrant/Swimming distance (Ratio)	0.44 ± 0.04	0.43 ± 0.05	0.21 ± 0.03^a	0.40 ± 0.03^b
Swimming time in quadrant (s)	20.36 ± 4.58	21.07 ± 4.11	13.59 ± 3.09^a	20.91 ± 4.07^b
Swimming time out of quadrant (s)	26.41 ± 4.17	28.29 ± 5.31	31.90 ± 6.78^a	27.15 ± 5.57^b
Swimming time in quadrant/Total swimming time (Ratio)	0.44 ± 0.06	0.43 ± 0.05	0.30 ± 0.03^a	0.45 ± 0.04^b
Latency (s)	19 ± 2.33	22 ± 2.58	35 ± 3.89^a	25 ± 2.66^b
Number of crossing platform	9.72 ± 1.37	10.13 ± 1.56	5.27 ± 1.42^a	8.89 ± 0.99^b
Swimming speed in quadrant (mm/s)	132.12 ± 21.57	121.97 ± 19.46	108.64 ± 13.51	118.27 ± 15.60
Swimming speed out quadrant (mm/s)	135.46 ± 14.47	134.68 ± 16.94	142.04 ± 15.48	130.02 ± 16.02
Average Swimming speed (mm/s)	133.26 ± 16.95	132.45 ± 19.83	135.33 ± 13.33	128.54 ± 16.46
MCA V_S (cm/s)	35.17 ± 4.29	36.09 ± 3.81	26.27 ± 3.89^a	33.14 ± 4.74^b
MCA V_d (cm/s)	21.07 ± 3.61	24.01 ± 3.74	13.75 ± 2.36^a	22.96 ± 3.59^b
PWV (cm/s)	275 ± 36	239 ± 31	749 ± 41^a	328 ± 39^b

The experimental protocols were described and graphical in Online Fig. S2A. The original recordings were presented Fig. 6A. Data are expressed as means ± SE. ^aP < 0.05 vs. WT. ^bP < 0.05 vs. WT plus HTL. A one-way ANOVA followed by Scheffe test was used to determine P value between two groups in this table.