Table 3.
Effects of exogenous MT-GCH1 (C141A) on Step-down and Step-through tests in HTL-fed mice.
| Groups | WT-GCH1 (Control) | MT-GCH1 | WT-GCH1 +HTL | MT-GCH1 +HTL |
|---|---|---|---|---|
| N | 10 | 13 | 12 | 15 |
| Step-down | ||||
| Latency | 178 ± 21 | 169 ± 25 | 57 ± 14a | 159 ± 26b |
| Number of errors | 0.83 ± 0.12 | 0.90 ± 0.17 | 3.81 ± 0.39a | 0.98 ± 0.15b |
| Step-through | ||||
| Latency | 186 ± 27 | 161 ± 19 | 29±8a | 157 ± 14b |
| Number of errors | 0.47 ± 0.12 | 0.49 ± 0.11 | 2.25 ± 0.08a | 0.58 ± 0.13b |
The experimental protocols were described and graphical in Online Fig. S5A. Data are expressed as means ± SE. aP < 0.05 vs. WT-GCH1. bP < 0.05 vs. WT-GCH1 plus HTL. A one-way ANOVA followed by Scheffe test was used to determine P value between two groups in this table.