Table 1.
Baseline characteristics of 51,558 eligible individuals by NRTI combination in HIV-positive individuals, CoVIHd Collaboration, Spain, February-December 2020
| TAF/FTC N = 20,432 (39.6%) | TDF/FTC N = 6,160 (11.9%) | ABC/3TC N = 13,715 (26.6%) | Other regimes N = 11,251 (21.8%) | |
|---|---|---|---|---|
|
| ||||
| Sex [N (%)] | ||||
| Men | 16,527 (80.9) | 4,856 (78.8) | 10,797 (78.7) | 8,623 (76.6) |
| Women | 3,905 (19.1) | 1,304 (21.2) | 2,918 (21.3) | 2,628 (23.4) |
| Age, years [Median (IQR)] | 49 (39 – 56) | 48 (39 – 55) | 51 (41 – 57) | 53 (45 – 58) |
| Transmission category [N (%)] | ||||
| Heterosexual contact | 4,652 (22.8) | 1,463 (23.7) | 3,218 (23.5) | 2,726 (24.2) |
| Homo/bisexual contact | 8,939 (43.7) | 2,221 (36.1) | 4,859 (35.4) | 3,741 (33.2) |
| Injecting drug use | 3,501 (17.1) | 1,242 (20.2) | 2,665 (19.4) | 2,847 (25.3) |
| Other | 503 (2.5) | 147 (2.4) | 300 (2.2) | 328 (2.9) |
| Unknown | 2,837 (13.9) | 1,087 (17.6) | 2,673 (19.5) | 1,609 (14.3) |
| Country of origin [N (%)] | ||||
| Spain | 12,632 (61.8) | 3,836 (62.3) | 8,553 (62.4) | 8,077 (71.8) |
| Other | 4,689 (22.9) | 1,367 (22.2) | 2,325 (16.9) | 1,568 (13.9) |
| Unknown | 3,111 (15.2) | 957 (15.5) | 2,837 (20.7) | 1,606 (14.3) |
| CD4 cell count, cells/mm3 | ||||
| Median (IQR) | 704 (509–933) | 700 (511–929) | 746 (536–994) | 718 (520–948) |
| <350 | 2,059 (10.1) | 619 (10.0) | 1,179 (8.6) | 1,014 (9.0) |
| 350–500 | 2,775 (13.6) | 834 (13.5) | 1,735 (12.6) | 1,504 (13.4) |
| >500 | 15,414 (75.4) | 4,671 (75.8) | 10,718 (78.1) | 8,620 (76.6) |
| Unknown | 184 (0.9) | 36 (0.6) | 83 (0.6) | 113 (1.0) |
| Hypertension [N (%)] | ||||
| No | 16,804 (82.2) | 5,388 (87.5) | 10,897 (79.4) | 8,469 (75.3) |
| Yes | 3,091 (15.1) | 695 (11.3) | 2,589 (18.9) | 2,564 (22.8) |
| Unknown | 537 (2.6) | 77 (1.2) | 229 (1.7) | 218 (1.9) |
| Diabetes [N (%)] | ||||
| ȀNo | 18,490 (90.5) | 5,707 (92.6) | 12,217 (89.1) | 9,736 (86.5) |
| Yes | 1,486 (7.3) | 380 (6.2) | 1,302 (9.5) | 1,305 (11.6) |
| Unknown | 456 (2.2) | 73 (1.2) | 196 (1.4) | 210 (1.9) |
| Chronic renal disease [N (%)] | ||||
| No | 19,375 (94.8) | 5,952 (96.6) | 12,570 (91.6) | 10,028 (89.1) |
| Yes | 1,057 (5.2) | 208 (3.4) | 1,145 (8.3) | 1,223 (10.9) |
| Cardiovascular disease [N (%)] | ||||
| No | 16,628 (81.4) | 5,511 (89.5) | 11,759 (85.7) | 9,568 (85.0) |
| Yes | 1,051 (5.1) | 302 (4.9) | 773 (5.6) | 887 (7.9) |
| Unknown | 2,753 (13.5) | 347 (5.6) | 1,183 (8.6) | 796 (7.1) |
| Treatment with immunosuppressants or corticosteroids [N (%) | ||||
| No | 13,631 (66.7) | 4,313 (70.0) | 8,768 (63.9) | 7,805 (69.4) |
| Yes | 174 (0.8) | 78 (1.3) | 163 (1.2) | 142 (1.3) |
| Unknown | 6,627 (32.4) | 1,769 (28.7) | 4,784 (34.9) | 3,304 (29.4) |