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. Author manuscript; available in PMC: 2023 Dec 1.
Published in final edited form as: AIDS. 2022 Aug 23;36(15):2171–2179. doi: 10.1097/QAD.0000000000003372

Appendix Table 6.

Unadjusted 48-week risk differences and risk ratios of COVID-19 outcomes by NRTI combination in HIV-positive individuals, CoVIHd Collaboration, Spain, February-December 2020

Documented SARS-CoV-2 infection Hospitalization due to COVID-19 ICU admission due to COVID-19 COVID-19 death
Risk Differences (95% CI), % Risk Ratios (95% CI) Risk Differences (95% CI), % Risk Ratios (95% CI) Risk Differences (95% CI), % Risk Ratios (95% CI) Risk Differences (95% CI), % Risk Ratios (95% CI)
TAF/FTC 0 1.00 0 1.00 0 1.00 0 1.00
TDF/FTC 0.35 (−0.29, 0.92) 1.08 (0.94, 1.21) −0.20 (−0.44, 0.01) 0.74 (0.48, 1.01) −0.05 (−0.10, 0.01) 0.39 (0.14, 1.21) −0.03 (−0.06, 0.02) 0.37 (0.22, 1.71)
ABC/3TC 0.49 (0.02, 0.95) 1.11 (1.00, 1.22) 0.30 (0.07, 0.50) 1.39 (1.09, 1.73) 0.05 (−0.02, 0.12) 1.58 (0.83, 3.16) 0.09 (0.03, 0.15) 2.98 (1.48, 8.62)
Other regimes −0.14 (−0.64, 0.37) 0.97 (0.86, 1.08) −0.0.004 (−0.20, 0.18) 0.99 (0.77, 1.28) −0.01 (−0.07, 0.05) 0.85 (0.29, 1.81) 0.04 (−0.02, 0.10) 1.82 (0.66, 4.58)