Table 2.
Frequency of Kenyan parasites harboring Pfpm2/3 and Pfmdr1 multiple copies between 2008 and 2021
| Study period | ||||||||
|---|---|---|---|---|---|---|---|---|
| 2008–2013 | 2014–2017 | 2018–2021 | P-value | |||||
| Genotype | N | Proportion | N | Proportion | N | Proportion | ||
| Pfmdr1 | Single copy | 57 | 98.3% | 122 | 96.1% | 92 | 96.8% | |
| Multi-copy | 1 | 1.7% | 5 | 3.9% | 3 | 3.2% | 0.7304 | |
| Pfpm2 | Single copy | 65 | 97.0% | 118 | 98.3% | 97 | 98.0% | |
| Mult-copy | 2 | 3.0% | 2 | 1.7% | 2 | 2.0% | 0.4522 | |
| Pfpm3 | Single copy | 80 | 89.9% | 100 | 93.5% | 96 | 96.0% | |
| Multi-copy | 9 | 10.1% | 7 | 6.5% | 4 | 4.0% | 0.8318 | |
Pfmdr1 Plasmodium falciparum multi-drug resistance 1 gene, Pfpm2 Plasmodium falciparum plasmepsin 2, Pfpm3 Plasmodium falciparum plasmepsin 3, N number of samples