Table 4.
Univariate analysis of the risk factors for severe adverse outcomes occurring after the diagnosis of PHD
| Valuables | Group A (n = 87) | Group B (n = 66) | P value |
|---|---|---|---|
| Preoperative factors | |||
| Age (years) | 51.26 ± 10.44 | 51.50 ± 10.78 | 0.892 |
| BMI (kg/m2) | 25.14 ± 3.23 | 25.50 ± 3.08 | 0.484 |
| Hypertension (n, %) | 61 (70.1) | 59 (89.4) | 0.004 |
| Diabetes mellitus (n, %) | 2 (2.3) | 5 (7.6) | 0.247 |
| Moderate/severe pericardial effusion (n, %) | 1 (1.1) | 8 (12.1) | 0.012 |
| Acute aortic regurgitation (n, %) | 24 (27.6) | 20 (30.3) | 0.713 |
| Preoperative renal insufficiency (n, %) | 11 (12.6) | 24 (36.9) | < 0.001 |
| Myocardial ischaemia (n, %) | 2 (2.3) | 5 (7.6) | 0.247 |
| Involving the celiac trunk (n, %) | 12 (13.8) | 21 (31.8) | 0.007 |
| Involving the renal artery (n, %) | 11 (12.6) | 14 (21.2) | 0.156 |
| Preoperative LVEF (%) | 63.40 ± 7.19 | 62.87 ± 7.81 | 0.661 |
| Intraoperative factors | |||
| Total operation time (min) | 301.33 (260.00,329.00) | 334.00 (272.25,366.75) | 0.008 |
| CPB time (min) | 144.05 (117.00,162.00) | 166.24 (130.00,173.75) | 0.009 |
| CPB time > 180 min | 9 (10.3) | 16 (24.2) | 0.021 |
| ACC time(min) | 48.97 (35.00,56.00) | 57.14 (37.75,68.75) | 0.170 |
| SBP time (min) | 9.29 ± 3.72 | 9.57 ± 3.39 | 0.638 |
| DHCA time (min) | 3.07 ± 1.72 | 2.79 ± 1.45 | 0.286 |
| Erythrocytes (U) | 4.37 ± 2.26 | 4.77 ± 2.31 | 0.286 |
| Plasma (ml) | 4.37 (2.00,6.00) | 4.77 (3.00,6.00) | 0.200 |
| Apheresis platelets(U) | 0.60 ± 0.45 | 0.59 ± 0.47 | 0.815 |
| Early postoperative factors | |||
| Leucocytes (109/L) | 13.94 ± 3.77 | 13.95 ± 4.02 | 0.983 |
| Hemoglobin (g/L) | 126.74 ± 17.44 | 123.08 ± 22.28 | 0.256 |
| Platelet (109/L) | 116.10 ± 55.08 | 96.70 ± 47.17 | 0.023 |
| Total bilirubin (U/L) | 54.08 ± 54.00 | 43.41 ± 29.37 | 0.149 |
| Albumin (g/L) | 39.48 ± 6.49 | 36.98 ± 6.81 | 0.022 |
| Alanine transaminase (U/L) | 135.74 (21.00,55.00) | 335.33 (22.75,203.25) | 0.187 |
| Aspartate transaminase (U/L) | 414.94 (52.00,130.00) | 890 (57.75,647.50) | 0.021 |
| γ-glutamyl transferase (U/L) | 36.36 (14.00,39.00) | 30.35 (17.00,36.25) | 0.730 |
| Alkaline phosphatase (U/L) | 55.98 ± 25.05 | 48.29 ± 16.27 | 0.032 |
| Serum creatinine (μmoI/L) | 154.33 (104.00,188.00) | 227.65 (132.75,276.25) | < 0.001 |
| Lactic acid (mmol/L) | 3.93 (1.60,5.40) | 5.31 (2.27,7.13) | 0.027 |
| 24-h postoperative drainage volume (mL) | 403.42 ± 264.35 | 605.03 ± 398.80 | < 0.001 |
Biochemical data are the maximum values within one week after surgery
Group A: No severe adverse outcomes occurrence after diagnosis of postoperative HD. Group B: severe adverse outcomes occurrence after diagnosis of postoperative HD