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. 2022 Nov 18;20:449. doi: 10.1186/s12916-022-02636-2

Table 2.

HRs and 95% CIs of individual coffee and tea consumption for all-cause and cause-specific mortality

Cause of death All participants Coffee consumption (cups/day) Tea consumption (cups/day)
None (N = 110,646) < 1–2 (N = 229,498) 3–4 (N = 102,694) ≥ 5 (N = 55,320) None (N = 73,223) < 1–1 (N = 57,438) 2–4 (N = 217,454) ≥ 5 (N = 150,043)
All causes
 No. of deaths (%) 34,699 7963 (22.95) 15,023 (43.30) 7124 (20.53) 4589 (13.23) 5681 (16.37) 3744 (10.79) 14,206 (40.94) 11,068 (31.90)
 Model 1a 1.00 (Ref.) 0.80 (0.78–0.83) 0.84 (0.81–0.86) 1.03 (0.99–1.07) 1.00 (Ref.) 0.84 (0.80–0.87) 0.77 (0.75–0.80) 0.86 (0.83–0.89)
 Model 2b 1.00 (Ref.) 0.91 (0.88–0.93) 0.92 (0.89–0.95) 0.97 (0.93–1.01) 1.00 (Ref.) 0.92 (0.88–0.96) 0.86 (0.83–0.88) 0.87 (0.84–0.90)
Cardiovascular disease
 No. of deaths (%) 6663 1528 (22.93) 2854 (42.83) 1366 (20.50) 915 (13.73) 1106 (16.60) 731 (10.97) 2748 (41.24) 2078 (31.19)
 Model 1a 1.00 (Ref.) 0.79 (0.74–0.84) 0.81 (0.75–0.88) 1.02 (0.94–1.12) 1.00 (Ref.) 0.84 (0.76–0.92) 0.77 (0.71–0.83) 0.82 (0.75–0.88)
 Model 2b 1.00 (Ref.) 0.94 (0.88–1.00) 0.96 (0.89–1.04) 1.04 (0.95–1.14) 1.00 (Ref.) 0.94 (0.85–1.03) 0.88 (0.81–0.94) 0.87 (0.80–0.94)
Respiratory disease
 No. of deaths (%) 6018 1532 (25.46) 2354 (39.12) 1173 (19.49) 959 (15.94) 1078 (17.91) 549 (9.12) 2247 (37.34) 2144 (35.63)
 Model 1a 1.00 (Ref.) 0.67 (0.63–0.71) 0.75 (0.69–0.81) 1.16 (1.06–1.26) 1.00 (Ref.) 0.68 (0.61–0.75) 0.69 (0.64–0.75) 0.92 (0.85–0.99)
 Model 2b 1.00 (Ref.) 0.84 (0.78–0.89) 0.90 (0.83–0.98) 1.06 (0.97–1.16) 1.00 (Ref.) 0.80 (0.72–0.88) 0.80 (0.74–0.87) 0.91 (0.84–0.99)
Digestive disease
 No. of deaths (%) 2864 768 (26.82) 1189 (41.52) 544 (18.99) 363 (12.67) 533 (18.61) 351 (12.26) 1155 (40.33) 825 (28.81)
 Model 1a 1.00 (Ref.) 0.66 (0.60–0.72) 0.60 (0.54–0.68) 0.72 (0.63–0.82) 1.00 (Ref.) 0.84 (0.73–0.96) 0.65 (0.58–0.72) 0.61 (0.55–0.69)
 Model 2b 1.00 (Ref.) 0.78 (0.71–0.86) 0.69 (0.62–0.78) 0.67 (0.59–0.77) 1.00 (Ref.) 0.95 (0.83–1.09) 0.76 (0.68–0.85) 0.65 (0.58–0.73)

Abbreviations: HR hazard ratio; CI confidence interval

aAdjusted for sex and age

bAdjusted for sex, age, ethnicity, education levels, BMI, smoking status, alcohol intake frequency, physical activity, dietary pattern, general health status, hypertension, diabetes, and depression. Coffee and tea consumption were mutually adjusted