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Adjusted estimates (95% confidence interval) of longitudinal trajectories of z‐scored cerebrospinal fluid (CSF) amyloid beta (Aβ)42/Aβ40 (top), phosphorylated tau (p‐tau181; middle) and total tau (t‐tau; bottom) biomarkers over time by, separately for apolipoprotein E (APOE) ε4 carriers (dashed tan lines) and non‐carriers (solid green lines). Results are shown using years since baseline (left) and chronological age (right) as the timescale
