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Adjusted estimates (95% confidence interval) of longitudinal trajectories of z‐scored cerebrospinal fluid (CSF) amyloid beta (Aβ)42/Aβ40 (top), phosphorylated tau (p‐tau181; middle) and total tau (t‐tau; bottom) biomarkers over time, separately for those who remained normal (solid green lines) versus progressed to mild cognitive impairment dementia (dashed tan lines). Results are modeled using years since baseline as the timescale
