Table 6. Comparison of QSAR Conclusions with Those of Readily/Inherently Biodegradable Screening Testsa.
| comparison of readily/inherently biodegradable tests (compiled) with various QSARs | QSAR maximum t1/2 (d) | n | |
|---|---|---|---|
| t1/2-QSAR | not readily/inherently biodegradable ANDt1/2-QSAR ≥ 28 days | 80% | 1365 |
| readily/inherently biodegradable ANDt1/2-QSAR < 28 days | 68% | 2159 | |
| overall efficiency | 73% | 3524 | |
| OPERA | not readily/inherently biodegradable AND OPERA ≥ 28 days | 16% | 1071 |
| readily/inherently biodegradable AND OPERA < 28 days | 95% | 1747 | |
| overall efficiency | 65% | 2818 | |
| BIOWIN-ECHA | not readily/inherently biodegradable agrees with the BIOWIN-ECHA PBT Guideline32 method for Potential P/vP | 34% | 1401 |
a
Overall efficiency refers to the frequency at which “Potential P/vP” and “Not P” were predicted correctly.