Table 2.
HRs (95% CIs) for AF Relative to BMI Group
Variable | Model 1* | Model 2† | Model 3‡ | Model 4§ |
---|---|---|---|---|
Events/population | 36 693/1 704 466 | 36 275/1 614 868 | 36 126/1 587 607 | 24 897/1 297 909 |
BMI <18.5 kg/m2 | 0.94 (0.90–0.98) | 0.94 (0.90–0.98) | 0.99 (0.95–1.04) | 1.00 (0.95–1.06) |
BMI 18.5–<20.0 kg/m2 | 1.00 | 1.00 | 1.00 | 1.00 |
BMI 20.0–<22.5 kg/m2 | 1.15 (1.12–1.19) | 1.14 (1.11–1.18) | 1.09 (1.05–1.12) | 1.06 (1.03–1.10) |
BMI 22.5–<25.0 kg/m2 | 1.43 (1.39–1.48) | 1.41 (1.36–1.46) | 1.29 (1.24–1.33) | 1.23 (1.18–1.28) |
BMI 25.0–<27.5 kg/m2 | 1.74 (1.66–1.81) | 1.69 (1.62–1.77) | 1.55 (1.48–1.62) | 1.45 (1.37–1.54) |
BMI 27.5–<30.0 kg/m2 | 2.28 (2.14–2.42) | 2.19 (2.06–2.33) | 2.03 (1.91–2.16) | 1.87 (1.73–2.02) |
BMI 30.0–<35.0 kg/m2 | 2.91 (2.71–3.11) | 2.76 (2.58–2.96) | 2.56 (2.39–2.75) | 2.39 (2.19–2.61) |
BMI 35.0–<40.0 kg/m2 | 3.75 (3.24–4.33) | 3.64 (3.14–4.22) | 3.41 (2.93–3.97) | 2.80 (2.30–3.40) |
BMI 40.0–50.0 kg/m2 | 4.70 (3.44–6.41) | 4.39 (3.13–6.15) | 4.30 (3.05–6.06) | 3.72 (2.44–5.66) |
Per unit BMI | 1.083 (1.080–1.087) | 1.080 (1.077–1.084) | 1.071 (1.068–1.075) | 1.064 (1.059–1.068) |
The HRs were derived from Cox regressions (Methods) with different models of adjustments as follows. AF indicates atrial fibrillation; BMI, body mass index; and HR, hazard ratio.
Model 1 adjusted for age at conscription, conscription year, and test center.
Model 2 as model 1, additionally adjusted for systolic and diastolic blood pressure at baseline, and baseline comorbidities diabetes, hypertension, and adult congenital heart disease.
Model 3 as model 2, additionally adjusted for cardiorespiratory fitness and muscle strength.
Model 4 as model 3, additionally adjusted for parental education and intelligence quotient.