Table 1.
All (n=162) | No MACE (n=133) | MACE (n=29) | P value | |
---|---|---|---|---|
Demographics (162/162) | ||||
Age (y) | 40 [27–54] | 35 [25–51] | 56 [44–67] | <0.001 |
Male | 121 (75) | 104 (78) | 17 (59) | 0.03 |
BMI (kg/m 2 ) | 25 ± 4 | 25 ± 4 | 26 ± 5 | 0.57 |
Medical history (162/162) | ||||
Atrial fibrillation | 4 (3) | 2 (2) | 2 (7) | 0.22 |
Pericarditis | 5 (3) | 4 (3) | 1 (3) | 1.00 |
Myocarditis | 9 (6) | 8 (6) | 1 (3) | 1.00 |
Hypertension | 26 (16) | 19 (14) | 6 (21) | 0.41 |
Hypercholesterolemia | 14 (9) | 7 (5) | 7 (24) | <0.01 |
Chronic obstructive pulmonary disease | 6 (4) | 5 (4) | 2 (7) | 0.61 |
Diabetes | 5 (3) | 2 (2) | 3 (10) | 0.04 |
Autoinflammatory disease | 24 (15) | 17 (13) | 7 (24) | 0.16 |
Clinical presentation (162/162) | ||||
Chest pain | 123 (76) | 109 (82) | 15 (52) | <0.01 |
Dyspnea | 56 (35) | 40 (30) | 14 (48) | 0.08 |
Collapse | 12 (7) | 7 (5) | 4 (14) | 0.12 |
Flulike symptoms | 98 (61) | 86 (65) | 12 (41) | 0.02 |
Fever | 58 (36) | 52 (39) | 6 (21) | 0.06 |
Use of toxic substances | 9 (6) | 5 (4) | 3 (10) | 0.16 |
Smoking status | 0.12 | |||
Never | 112 (69) | 85 (64) | 23 (79) | |
Former smoker | 20 (12) | 16 (12) | 5 (17) | |
Current smoker | 30 (19) | 29 (22) | 1 (3) | |
Heart rate (bpm) | 87 ± 27 | 85 ± 22 | 99 ± 44 | 0.02 |
Systolic blood pressure (mm Hg) | 128 ± 24 | 129 ± 24 | 122 ± 22 | 0.22 |
Diastolic blood pressure (mm Hg) | 78 ± 16 | 79 ± 16 | 76 ± 17 | 0.42 |
Killip class | 0.05 | |||
Class I | 141 (87) | 119 (89) | 22 (76) | |
Class II | 15 (9) | 9 (7) | 4 (14) | |
Class III | 1 (1) | 0 | 1 (3) | |
Class IV | 5 (3) | 3 (2) | 2 (7) | |
Laboratory findings | ||||
Creatinine (μmol/L) at admittance (n=159) | 77 [68–91] | 77 [69–90] | 83 [70–104] | 0.11 |
Elevated troponin (%) (n=154) | 147 (91) | 121 [92] | 25 [86] | 0.16 |
Creatine kinase, maximum (U/L) (n=142) | 395 [163–836] | 482 [218–886] | 155 [85–324] | <0.01 |
NTproBNP, maximum (pmol/L) (n=58) | 506 [72–3071] | 371 [57–1693] | 3600 [335–10 473] | 0.02 |
Leucocytes, maximum (10E9/L) (n=156) | 10.9 [8.0–14.2] | 10.9 [7.9–13.8] | 10.4 [7.4–15.4] | 0.13 |
C‐reactive protein, maximum (mg/L) (n=156) | 45 [15–123] | 45 [18–129] | 26 [6–113] | 0.01 |
Electrocardiography (162/162) | ||||
Conduction disorders | ||||
High degree AV‐block (2nd or 3rd degree) | 1 (1) | 1 (1) | 0 | 1.00 |
Left bundle branch block | 6 (4) | 3 (2) | 3 (10) | 0.08 |
Right bundle branch block | 6 (4) | 5 (4) | 1 (3) | 1.00 |
ST‐segment elevation | 88 (54) | 77 (58) | 12 (41) | 0.14 |
ST‐segment depression | 38 (24) | 34 (26) | 5 (17) | 0.47 |
Genetic testing | ||||
Performed | 12 (7) | 6 (5) | 6 (21) | 0.008 |
Pathogenic or likely pathogenic mutation | 2 (1) | 1 (1) | 1 (3) | |
Admission (162/162) | ||||
Admission duration (days) | 7 [4–11] | 6 (4–10) | 9 (6–16) | 0.01 |
Transfer to intensive care unit | 18 (11) | 15 (11) | 3 (10) | 1.00 |
Start of immunosuppressive therapy | 23 (14) | 18 (14) | 5 (17) | 0.57 |
Data are presented as mean ± standard deviation, median (interquartile range) or number (%).
Abbreviations: BMI indicates body mass index; and MACE, major adverse cardiovascular event.