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. 2022 Nov 16;38(1):203–215. doi: 10.1080/14756366.2022.2142786

Scheme 1.

Scheme 1.

Synthesis of 4-chloro-1-phenyl-1H-pyrazolo[3,4-d]pyrimidine 4. Reagents and conditions: A = Phenyl hydrazine, ethanol, 80° C, 4 h. B = HCONH2, 190° C, 8 h. C = POCI3, 106° C, 6 h.