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. 2022 Nov 14;17:5265–5286. doi: 10.2147/IJN.S369761

Table 2.

Drug Release Kinetic Parameters and Fitting Coefficients

Zero Order Equation First-Order Equation Higuchi’s Equation
r2 k0 r2 k1 r2 kh
PTX 0.7620 0.5097 0.9514 0.0711 0.9124 7.2999
PTX-SLN@CUD 0.9682 0.4839 0.9664 0.0068 0.9100 6.3691

Notes: r2, fitting coefficient; K0, K1, and Kh are the rate constants for the zero-order, first-order, and Higuchi equations, respectively.