Table 4.

IC₅₀ Values of PTX, CUD-LN and PTX-SLN@CUD Against MCF-7 Tumor Cells and Normal Hepatocytes L02 at 24 h, 48 h, 72 h and 96 h

Cells	Group	IC50 (μg/mL)
		24 h	48 h	72h	96h
MCF-7	PTX	>80	64.29±5.73	26.25±2.68	12.66±0.97
	CUD-LN	–	–	–	–
	PTX-SLN@CUD	>80	75.5±4.19	18.25±1.37	8.172±0.73
L02	PTX	>80	>80	36.86±3.18	17.34±0.83
	CUD-LN	–	–	–	–
	PTX-SLN@CUD	>80	>80	>80	>80

Note: since the inhibition of MCF-7 and L02 cells by CUD-LN at any concentration at each time point was very low (< 15%), the corresponding IC50 values could not be calculated.

Abbreviation: IC₅₀, half maximal inhibitory concentration.