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. 2022 Oct 1;56(3):155–171.

Table 6.

Interpretation of common measurements used in research studies

Measurement

Use

Limitations

Magnitude of associationa

Odds ratio (OR)

Determines the association between 2 variables (exposure to outcome)

Can be used in any study type but not always useful as it exaggerates the risk

OR 1.0 to 1.5 (further research required)

OR 1.5 < 2.0 (worth further investigation)

OR 2 < 4 (possibly important)

OR 4.0 (pretty strong)

Risk ratio/Relative risk (RR)

Determines risk of the incidence of an exposure to the incidence without the exposure

Study design must be representative of the population; cannot be used on case–control studies

Note: RR is a more accurate and preferable measure of risk

RR 1.0 to 1.5 (further research required)

RR 1.5 < 2.0 (worth further investigation)

RR 2.0 < 4.0 (possibly important)

RR 4.0 (pretty strong)

Hazard ratio (HR)

Determines how 1 group changes over another; based on rate of change between 2 hazards; typically used in survival studies

Usefulness based on consistency in the rate of change within 2 groups; used to measure certain “points in time”; does not measure “means” over time

HR 1 (no association)

HR 1.5 < 2.0 (weak association)

HR 2.5 < 3.5 (moderate association)

HR 3.5 (strong association)

Confidence interval (CI)

Intervals in which the population statistic could lie; typically uses a 95% confidence interval as the threshold for significant results. (Provides a range of values between which the results lie)

N/A

Range of values will be based on the OR, RR or HR measured and thus interpreted according to the above scales

The narrower the CI, the more precise the estimate

P value

Reports the probability that the sample statistic was produced from random sampling of a population

Significance values are determined by the researchers prior to commencement of the study set at a minimum of <0.05 (<5% probability that results are due to chance)

N/A

Significance based on what the researchers determined at the beginning of the study; no higher than p < 0.05

Table adapted from George A, Stead TS, Ganti L. What’s the risk: differentiating risk ratios, odds ratios and hazard ratios? Cureus. 2020;12(8):e10047.

aMagnitude of association adapted from http://utstat.utoronto.ca/reid/odds.pdf and http://onbiostatistics.blogspot.com