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. Author manuscript; available in PMC: 2022 Nov 18.
Published in final edited form as: Nature. 2017 Jul 19;547(7664):419–424. doi: 10.1038/nature23262

Extended data figure 5. Androgenetic (AG)- and gynogenetic (GG)-specific DHSs in morula embryos, related to Figure 3.

Extended data figure 5.

a, Scatter plot showing the correlation between biological duplicates of liDNase-seq for AG and GG morula embryos.

b, Averaged SNP-tracked liDNase-seq signal intensity of paternal and maternal alleles in hybrid morula embryos. The data were obtained from morula embryos of a BDF1 and JF1 cross 7. Plots from the biological duplicates (e.g. BDF1_1 and BDF1_2) are shown. Note that paternal (JF1), but not maternal (BDF1), SNP reads are enriched in AG-DHSs (left panel), while neither SNP reads are enriched in GG-DHSs (right panel).

c, Genome browser view of DHSs at known imprinting control regions (ICRs). The genomic locations of ICRs were defined previously 9.

d, Pie chart showing AG-DHSs grouped based on their oocyte DNA methylation levels.