Table 2. Clinical and CMR characteristics in NICM patients with vs. without impaired myocardial perfusion reserve index.
MPRI >1.51 (N = 22) | MPRI <1.51 (N = 30) | P-value | ||
---|---|---|---|---|
Clinical Characteristics | ||||
Age (years) | 52 (33–61) | 57 (38–63) | 0.37 | |
Gender, N (% male) | 13 (72%) | 11 (48%) | 0.11 | |
Ethnicity | White, N (%) | 13 (72%) | 15 (65%) | 0.32 |
Black, N (%) | 4 (22%) | 8 (35%) | ||
Hispanic, N (%) | 1 (6%) | 0 (0%) | ||
Other, N (%) | 0 (0%) | 0 (0%) | ||
Diabetes, N (%) | 2 (11%) | 4 (17%) | 0.57 | |
Hypertension, N (%) | 7 (39%) | 17 (74%) | 0.02 | |
Hyperlipidemia, N (%) | 6 (33%) | 10 (43%) | 0.51 | |
Atrial Fibrillation/Flutter, N (%) | 1 (6%) | 2 (9%) | 0.70 | |
Creatinine (mg/dL) | 0.90 (0.79–1.12) | 0.84 (0.75–1.05) | 0.67 | |
Hematocrit (%) | 39 ± 7 | 37 ± 5 | 0.29 | |
B-type Natriuretic Peptide (ng/L) | 206 (28–1500) | 69 (39–682) | 0.70 | |
Troponin-I (ng/mL) | 0 (0–0.04) | 0.01 (0–0.05) | 0.61 | |
CMR Characteristics | ||||
LVEDD (cm) | 5.7 (5.1–6.5) | 5.6 (5.3–6.2) | 0.75 | |
LVEDV (mL) | 185 (158–226) | 177 (153–212) | 0.73 | |
LVEDV Indexed (mL/m2) | 100 (68–105) | 87 (70–108) | 0.89 | |
LVESV (mL) | 113 (91–130) | 106 (79–152) | 1.0 | |
LVESV Indexed (mL/m2) | 55 (40–65) | 56 (41–76) | 0.77 | |
LVEF (%) | 42 (38–46) | 43 (30–45) | 0.63 | |
LA Volume Indexed (gm/m2) | 43 (36–65) | 46 (44–58) | 0.63 | |
LV mass (gm) | 109 (86–129) | 113 (83–135) | 0.77 | |
LV mass Indexed (gm/m2) | 49 (45–63) | 58 (46–64) | 0.38 | |
LGE presence (%) | 11 (61%) | 10 (48%) | 0.26 | |
Number of segments | 2 (0–3) | 0 (0–2) | 0.24 |
MPRI: myocardial perfusion reserve index; LV: left ventricle; EDD: end diastolic dimension; EDV: end diastolic volume; EF: ejection fraction; ESV: end systolic volume; LA: left atrium; LGE: late gadolinium enhancement.