Fig. 3.

Scoring based on deep learning and clinical data. (A) Schematics of training a deep learning–based TIL score analyzer using 411 patient tumor H&E images with correlated patient survival information from the TCGA database. (B) Schematics show the screening of a library of 141 small-molecule epigenetic modulators. Our automated system tracks the T cell tumor infiltration images for each drug, extracts the T cell map, assigns TIL score_i (e.g., 0, 1) for each image, and generates a final TIL score for drug X by averaging multiple TIL score_i from the drug treatment images.