Skip to main content
. 2022 Nov 11;119(46):e2203491119. doi: 10.1073/pnas.2203491119

Fig. 5.

Fig. 5.

Example genes with sex-biased DNV pattern. Linear protein diagrams are plotted in same way as in Fig. 4. Number of samples plotted: female (n = 16,530) and male (n = 29,704). (A) DDX3X and (B) HDAC8 DNVs are almost exclusively in females and with female-only DNV burden and enrichment significance. (C) FBN1 and (D) KMT2E, while having no sex-biased DNV burden significance, show male-specific DNV enrichment significance and more DNVs in males than females.