Fig. 7. Mitochondrial AGA and AGG act as nonstop codons in gene expression.

(A) Top: Schematic of the human MT-CO1 and the 3′ DNA sequence. Bottom left: Analysis of the 3′ codon in the CDS of MT-CO1 from 109 primate species of the suborder Haplorhini. Bottom right: The predicted 3′ codon following a −1 ribosome frameshift on the AGA and AGG codons. (B) The same analysis as in (A) for MT-ND6.