TABLE 2.
Associations With OOP Costs
| OOP Costs in the Past 30 d, $ | OOP Costs in the Past Year, $ | |||||||
|---|---|---|---|---|---|---|---|---|
| Variable, n (%) | ≥100 | P | ≥200 | P | Median (Min–Max) | P | ≥1000 | P |
| Current AD severity | ||||||||
| Clear | 5 (20.0) | <0.0001 | 3 (12.0) | <0.0001 | 500 (0–5000) | <0.0001 | 6 (28.6) | <0.0001 |
| Mild | 44 (20.3) | 18 (8.3) | 360 (0–15,000) | 49 (26.5) | ||||
| Moderate | 135 (28.9) | 62 (13.3) | 500 (0–200,000) | 159 (38.5) | ||||
| Severe | 122 (45.5) | 73 (27.2) | 1000 (16–23,000) | 144 (62.1) | ||||
| Current AD control | ||||||||
| Minimally controlled | 94 (41.1) | 0.0004 | 54 (23.6) | 0.003 | 600 (0–200,000) | 0.16 | 87 (43.5) | 0.66 |
| Somewhat controlled | 124 (31.0) | 60 (15.0) | 600 (0–25,000) | 155 (43.4) | ||||
| Moderately well controlled | 76 (27.9) | 32 (11.8) | 500 (0–23,000) | 93 (40.8) | ||||
| Very well controlled | 15 (17.1) | 11 (12.5) | 500 (0–100,000) | 28 (36.4) | ||||
| No. flare days in the past 30 d | ||||||||
| 0 | 11 (27.5) | <0.0001 | 8 (20.0) | 0.0004 | 300 (0–5,000) | <0.0001 | 10 (30.3) | 0.0007 |
| 1–3 | 50 (21.0) | 20 (8.4) | 500 (0–100,000) | 74 (34.4) | ||||
| 4–7 | 56 (29.3) | 24 (12.6) | 500 (50–25,000) | 67 (39.9) | ||||
| 8–10 | 40 (28.6) | 21 (15.0) | 500 (50–15,000) | 44 (36.4) | ||||
| ≥11 | 153 (39.4) | 84 (21.7) | 1000 (0–200,000) | 169 (51.1) | ||||
| Comorbidities | ||||||||
| Asthma | 117 (33.8) | 0.23 | 59 (17.1) | 0.51 | 800 (0–200,000) | 0.002 | 146 (48.8) | 0.002 |
| Allergic rhinitis | 168 (33.0) | 0.22 | 86 (16.9) | 0.45 | 775 (0–200,000) | <0.0001 | 207 (47.5) | 0.0007 |
| Food allergy | 139 (36.4) | 0.008 | 83 (21.7) | <0.0001 | 1000 (2–200,000) | <0.0001 | 185 (55.7) | <0.0001 |
| Frequent/persistent skin infections | 73 (38.4) | 0.022 | 44 (23.2) | 0.003 | 1000 (2–200,000) | <0.0001 | 98 (60.1) | <0.0001 |
| Anxiety and/or depression | 121 (32.6) | 0.44 | 62 (16.7) | 0.58 | 800 (0–200,000) | 0.01 | 154 (48.4) | 0.002 |
| HCP visits in the past year | ||||||||
| 0 | 7 (6.9) | <0.0001 | 3 (2.9) | <0.0001 | 250 (0–3,000) | <0.0001 | 12 (15.2) | <0.0001 |
| 1–2 | 82 (20.5) | 36 (9.0) | 500 (0–23,000) | 98 (27.5) | ||||
| 3–4 | 110 (40.9) | 49 (18.2) | 1000 (20–200,000) | 116 (50.2) | ||||
| ≥5 | 112 (49.8) | 70 (31.1) | 1200 (2–20,000) | 137 (68.2) | ||||
| No. treatments | ||||||||
| 0 | 21 (20.6) | <0.0001 | 6 (5.9) | <0.0001 | 300 (0–5,000) | <0.0001 | 15 (19.2) | <0.0001 |
| 1–2 | 60 (19.0) | 19 (6.0) | 400 (0–20,000) | 66 (23.3) | ||||
| ≥3 | 230 (39.7) | 133 (22.9) | 1000 (0–200,000) | 283 (55.7) | ||||
| Step-up therapy | ||||||||
| No | 136 (23.3) | <0.0001 | 60 (10.3) | <0.0001 | 500 (0–25,000) | <0.0001 | 169 (33.5) | <0.0001 |
| Yes | 172 (42.3) | 98 (24.1) | 1000 (0–200,000) | 190 (53.1) | ||||
AD, atopic dermatitis; HCP, health care provider; OOP, out-of-pocket.