Supplementary File 2.

Full search strategy

# 4	207	#3 AND #2 AND #1 Indexes=SCI-EXPANDED, ESCI Timespan=All years
# 3	17, 632	TS = (“single embryo transfer” or “embryo transfer” or “embryo transplantation” or “transfer, embryo” or “blastocyst transfer” or “embryo transfers” or “transfers, embryo” or “tubal embryo stage transfer” or “tubal embryo transfer”) Indexes=SCI-EXPANDED, ESCI Timespan=All years
# 2	42, 094	TS = (“sperm injections, intracytoplasmic “ or “injection, intracytoplasmic sperm” or “injections, intracytoplasmic sperm” or “injections, sperm, intracytoplasmic” or “intracytoplasmic sperm injection” or “intracytoplasmic sperm injections” or “sperm injection, intracytoplasmic” or “intracytoplasmic sperm injection” or “ICSI” or “intra cytoplasmic sperm injection “ or “babies, test-tube” or “baby, test-tube” or “fertilization, test-tube” or “fertilizations in vitro” or “fertilization in vitro” or “fertilizations, test-tube” or “extracorporeal fertilization” or “in vitro fertilization” or “in vitro fertilization” or “IVF (in vitro fertilization)” or “in vitro fertilizations” or “test tube babies” or “test tube fertilization” or “test-tube babies” or “test-tube baby” or “test-tube fertilization” or “test-tube fertilizations”) Indexes=SCI-EXPANDED, ESCI Timespan=All years
# 1	242, 623	TS = (“polymorphism, single nucleotide” or “nucleotide polymorphism, single” or “nucleotide polymorphisms, single” or “polymorphisms, single nucleotide” or “SNPs” or “single nucleotide polymorphism” or “single nucleotide polymorphisms” or “single nucleotid polimorphism” or “array based comparative genomic hybridization” or “array comparative genomic hybridization” or “array-based comparative genomic hybridization” or “comparative genome hybridization” or “comparative genome hybridizations” or “comparative genomic hybridizations” or “genome hybridization, comparative” or “genome hybridizations, comparative” or “genomic hybridization, comparative” or “genomic hybridizations, comparative” or “hybridization, comparative genome” or “hybridization, comparative genomic” or “hybridizations, comparative genome” or “hybridizations, comparative genomic” or “comparative genomic hybridization” or “metaphase comparative genomic hybridization” or “next generation secuencing” or “DNA sequencing, high-throughput” or “deep sequencing” or “deep sequencings” or “high throughput DNA sequencing” or “high throughput nucleotide sequencing” or “high throughput RNA sequencing” or “high-throughput DNA sequencing” or “high-throughput RNA sequencing” or “Illumina sequencing” or “Ion proton sequencing” or “Ion torrent sequencing” or “massively parallel sequencing” or “massively-parallel sequencing” or “next generation sequencing” or “next-generation sequencing” or “nucleotide sequencing, high-throughput” or “pyrosequencing” or “RNA sequencing, high-throughput” or “sequencing, deep” or “sequencing, high-throughput DNA” or “sequencing, high-throughput nucleotide” or “sequencing, high-throughput RNA” or “sequencing, Illumina” or “sequencing, Ion proton” or “sequencing, Ion torrent” or “sequencing, massively-parallel” or “sequencing, next-generation “ or “high-throughput nucleotide sequencing” or “quantitative PCR” or “quantitative polymerase chain reaction” or “quantitative polymerase chain reaction”) Indexes=SCI-EXPANDED, ESCI Timespan=All years

OVID Ovid MEDLINE(R) ALL 1946 to July 31, 2020 Embase 1974 to 2020 July 31
1	(“polymorphism, single nucleotide” or “nucleotide polymorphism, single” or “nucleotide polymorphisms, single” or “polymorphisms, single nucleotide” or “SNPs” or “single nucleotide polymorphism” or “single nucleotide polymorphisms” or “single nucleotide polymorphisms” or “array based comparative genomic hybridization” or “array comparative genomic hybridization” or “array-based comparative genomic hybridization” or “comparative genome hybridization” or “comparative genome hybridizations” or “comparative genomic hybridizations” or “genome hybridization, comparative” or “genome hybridizations, comparative” or “genomic hybridization, comparative” or “genomic hybridizations, comparative” or “hybridization, comparative genome” or “hybridization, comparative genomic” or “hybridizations, comparative genome” or “hybridizations, comparative genomic” or “comparative genomic hybridization” or “metaphase comparative genomic hybridization” or “next generation sequencing” or “DNA sequencing, high-throughput” or “deep sequencing” or “deep sequencings” or “high throughput DNA sequencing” or “high throughput nucleotide sequencing” or “high throughput RNA sequencing” or “high-throughput DNA sequencing” or “high-throughput RNA sequencing” or “Illumina sequencing” or “Ion proton sequencing” or “Ion torrent sequencing” or “massively parallel sequencing” or “massively-parallel sequencing” or “next generation sequencing” or “next-generation sequencing” or “nucleotide sequencing, high-throughput” or “pyrosequencing” or “RNA sequencing, high-throughput” or “sequencing, deep” or “sequencing, high-throughput DNA” or “sequencing, high-throughput nucleotide” or “sequencing, high-throughput RNA” or “sequencing, Illumina” or “sequencing, Ion proton” or “sequencing, Ion torrent” or “sequencing, massively-parallel” or “sequencing, next-generation” or “high-throughput nucleotide sequencing” or “quantitative PCR” or “quantitative polymerase chain reaction” or “quantitative polymerase chain reaction”). mp. [mp=ti, ab, hw, tn, ot, dm, mf, dv, kw, fx, dq, nm, kf, ox, px, rx, an, ui, sy]	661499
2	(“sperm injections, intracytoplasmic” or “injection, intracytoplasmic sperm” or “injections, intracytoplasmic sperm” or “injections, sperm, intracytoplasmic” or “intracytoplasmic sperm injection” or “intracytoplasmic sperm injections” or “sperm injection, intracytoplasmic” or “intracytoplasmic sperm injection” or “ICSI” or “intra cytoplasmic sperm injection” or “babies, test-tube” or “baby, test-tube” or “fertilization, test-tube” or “fertilizations in vitro” or “fertilization in vitro” or “fertilizations, test-tube” or “extracorporeal fertilization” or “in vitro fertilization” or “in vitro fertilization” or “IVF (in vitro fertilization)” or “in vitro fertilizations” or “test tube babies” or “test tube fertilization” or “test-tube babies” or “test-tube baby” or “test-tube fertilization” or “test-tube fertilizations”). mp. [mp=ti, ab, hw, tn, ot, dm, mf, dv, kw, fx, dq, nm, kf, ox, px, rx, an, ui, sy]	118432
3	(“single embryo transfer” or “embryo transfer” or “embryo transplantation” or “transfer, embryo” or “blastocyst transfer” or “embryo transfers” or “transfers, embryo” or “tubal embryo stage transfer” or “tubal embryo transfer”).mp. [mp=ti, ab, hw, tn, ot, dm, mf, dv, kw, fx, dq, nm, kf, ox, px, rx, an, ui, sy]	55491
4	1 and 2 and 3 Embase <1974 to 2020 July 31> Ovid MEDLINE(R) ALL <1946 to July 31, 2020>	781 533 248