Skip to main content
. 2022 Nov 14;8(11):e11622. doi: 10.1016/j.heliyon.2022.e11622

Figure 4.

Figure 4

Acteoside suppresses the protein concentration and cell counts in BALF and inhibits neutrophil infiltration in lung tissues. Mice were orally pretreated with different concentrations (100, 50, and 20 mg/kg/day) of acteoside or PDTC (100 mg/kg/day) or vehicle for 7 days. On the seventh day, CVF (35 μg/kg) was administered via tail vein injection for 1 h, and lung tissues and BALF were then collected. The total protein concentration (A) and cell counts (B) in BALF were assessed. The superior and middle lobe of the right lung was excised to detect lung MPO activity (C). Results were presented as mean ± SEM (n = 8). ##P < 0.01 was compared with the control group; ∗P < 0.05 and ∗∗P < 0.01 were compared with the CVF group. BALF, bronchoalveolar lavage fluid; PDTC, pyrrolidinedithiocarbamic acid; CVF, cobra venom factor; MPO, myeloperoxidase; SEM, standard error of the mean.