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. 2022 Nov 15;38:190–202. doi: 10.1016/j.jot.2022.05.005

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© 2022 Published by Elsevier (Singapore) Pte Ltd on behalf of Chinese Speaking Orthopaedic Society.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Influence of STE on the synthesis of ECM. The protein expression of collagen II, aggrecan, ADAMTS-4, and MMP-13 in the chondrocytes was detected by western blot analysis (A–E). Immunofluorescence for the assessment of Type II collagen (Col II) in mouse chondrocytes (F-G). Data were expressed as mean ± SD. ##P < 0.01 compared to the control group; ∗∗P < 0.01 compared to the IL-1β alone stimulation group, n = 3.

Influence of STE on the synthesis of ECM. The protein expression of collagen II, aggrecan, ADAMTS-4, and MMP-13 in the chondrocytes was detected by western blot analysis (A–E). Immunofluorescence for the assessment of Type II collagen (Col II) in mouse chondrocytes (F-G). Data were expressed as mean ± SD. ##P < 0.01 compared to the control group; ∗∗P < 0.01 compared to the IL-1β alone stimulation group, n = 3.