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. 2022 Nov 15;38:190–202. doi: 10.1016/j.jot.2022.05.005

Figure 7.

Figure 7

STE inhibits the OA process (A) The digital X-ray images of mouse knee joints (B) The Safranin O staining of cartilage shows STE alleviated the cartilage erosion and depletion of proteoglycans in mouse OA model at 8 weeks post-surgery (scale bar: 50 ​μm) (C) OARSI scores. The immunohistochemistry of Nrf2, MMP-13 and quantification of Nrf2-positive cells (B, D, E) (scale bar: 50 ​μm). Data were expressed as mean ​± ​SD. ##P ​< ​0.01, compared to the sham group; ∗∗P ​< ​0.01 compared to the DMM group, n ​= ​15.