Table 2.
Clinical, immunological and treatment-related characteristics of adults receiving ART following ‘Test and Treat strategy” in Bahir dar city, Northwest Ethiopia, November 2016 to December 2021.
Variables (N= 1020) | Categories | Failure status |
Frequency | % | |
---|---|---|---|---|---|
Event | Censored | ||||
Time to ART initiation | Within 7 days | 203 | 373 | 576 | 56.5 |
After 7 day | 97 | 347 | 444 | 43.5 | |
baseline WHO clinical stage | Stage I and II | 178 | 491 | 669 | 65.5 |
Stage III and IV | 122 | 229 | 351 | 34.5 | |
baseline CD4 category | Greater than 500 | 62 | 157 | 219 | 21.3 |
From 200 to 499 | 109 | 304 | 413 | 40.5 | |
<200 | 129 | 259 | 398 | 38.2 | |
Baseline BMI category | Underweight | 95 | 181 | 276 | 27.1 |
Normal and/or overweight | 205 | 539 | 744 | 72.9 | |
Functional status | Working | 224 | 570 | 794 | 77.8 |
Ambulatory | 58 | 120 | 178 | 17.5 | |
Bedridden | 18 | 30 | 48 | 4.7 | |
History of TB/HIV co-infection | Yes | 68 | 143 | 215 | 21.1 |
No | 232 | 577 | 805 | 78.9 | |
History of OIs | Yes | 120 | 243 | 363 | 35.5 |
No | 180 | 477 | 657 | 64.5 | |
Baseline ART regimen | 1e (TDF_3TC_EFV) | 234 | 486 | 723 | 70.9 |
1j (TDF_3TC- DTG) | 29 | 167 | 193 | 18.9 | |
Others | 37 | 67 | 104 | 10.2 | |
History of treatment failure | Yes | 17 | 39 | 56 | 5.5 |
No | 283 | 681 | 964 | 94.5 | |
History of regimen change | Yes | 75 | 190 | 265 | 26 |
No | 225 | 530 | 755 | 74 | |
History of side effects | Yes | 49 | 39 | 88 | 8.6 |
No | 251 | 681 | 932 | 91.4 | |
CPT prophylaxis status | Received | 152 | 378 | 530 | 52 |
Not-received | 148 | 342 | 490 | 48 | |
IPT prophylaxis status | Received | 157 | 440 | 597 | 58.5 |
Not_ received | 143 | 280 | 423 | 41.5 |
Others:- include 1c(AZT-3TC-NVP), 1d(AZT-3TC-EFV), 1f(TDF-3TC-NVP).
ART - Anti-retroviral Therapy, CD4+ cells - Cluster of differentiation cells, CPT-Cotrimoxsazole preventive therapy, IPT- Isoniazid preventive therapy, OIs-opportunistic infections, TB - tuberculosis.