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Reclassification of variants in Shariant
Number of unique variants that were reclassified from August 2019 to December 2021. Initial classification is represented on the x axis, and the number of each pathogenicity for reclassified variants is displayed via the colored bars. Most variants that changed classification were initially VUS (n = 73; 72%), and the majority of these resolved to likely pathogenic or pathogenic (n = 54, 74% of this subgroup).
