Table 1.

A sample descriptive adaptation matrix mobile health First Episode Digital Monitoring.

Domain		Stakeholder input and feedback	Suggestion for adapted practice	Varies by site	Relevant stakeholder quote	Adaptation implemented
App-related
	Questions or content	Current app content is fine, but weight gain should be added as a side effect	Add weight gain to the app questions	No	“Would you consider adding weight gain to the list of side-effects? Because that’s been something that has been brought up by some participants in the past and the prescriber really tries to, to work with them on that.”	Yes
	Pinging and frequency	10 pings a day may be too much	Reduce pings per day	N/Aa	“I’m just curious if like if you’re in college, you’re in high school; like how realistic is it that you’re going to be...? I don’t know what’s the frequency...”	No
Report
	Layout or design	Inclusion of daily averages is useful	Include daily averages in granular graph	No	“I like having the average for the day.”	Yes
	Access to report	It would be helpful for participants to receive a report of their answers within the app itself	Consider providing report directly to participant	No	“Just wondering, like are, are participants able to get like information like this?... like maybe like since it’s an app like they’re able to like see what they said and like past months.”	No, consider for future iteration
	Content	Caffeine should be included owing to its effects on sleep	Include caffeine as a substance	No	“[Caffeine and other substances] are relevant for sleep.”	Yes

^aN/A: not applicable.