Table 2.

Diagnostic accuracy of PF ADA and LDH/ADA ratio

Testing	AUC (95% CI)	Threshold	Sensitivity (95% CI)	Specificity (95% CI)
The BUFF study
LDH/ADA	0.74 (0.67–0.81)	20	0.74 (0.63–0.84)	0.66 (0.60–0.73)
ADA	0.76 (0.69–0.82)	35 U/L	0.47 (0.34–0.60)	0.86 (0.80–0.90)
The SIMPLE study
LDH/ADA	0.85 (0.76–0.93)	20	0.85 (0.70–0.97)	0.67 (0.60–0.74)
ADA	0.80 (0.71–0.90)	35 U/L	0.61 (0.45–0.76)	0.92 (0.88–0.96)

Abbreviations have been explained in the footnote of Table 1