Table 3.

Net reclassification improvement (NRI) and integrated discrimination improvement (IDI) analysis

Cohort	Continuous NRI		IDI
	Estimates (95% CI)	p	Estimates (95% CI)	p
The BUFF study	− 0.23 (− 0.51–0.05)	0.104	− 0.016 (− 0.040–0.008)	0.185
The SIMPLE study	0.06 (− 0.30–0.43)	0.726	0.013 (− 0.036–0.062)	0.606
All	− 0.09 (− 0.32–0.13)	0.413	− 0.012 (− 0.035–0.011)	0.294

ADA was set as a reference, and the added diagnostic value of LDH/ADA was analyzed with IDI and continuous NRI