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. 2022 Nov 19;22:722. doi: 10.1186/s12888-022-04378-0

Table 2.

Estimated associations between demographic/clinical variables and post-stroke depression (PHQ-9 ≥ 5) at follow-up (N = 307)

OR (95% CI) P value Adjusted OR (95% CI)a P value
Demographics
 Age 0.99 (0.98–1.01) 0.335 0.98 (0.96–1.00) 0.11
 Sex (female) 1.11 (0.71–1.75) 0.638 0.72 (0.37–1.43) 0.35
Race
  White 1 1
  Black 0.79 (0.48–1.32) 0.375 0.75 (0.35–1.62) 0.47
  Asian 2.38 (0.24–23.30) 0.455 0.56 (0.01–55.12) 0.81
  Native American 0.79 (0.05–12.88) 0.872 - -
 Married 0.84 (0.53–1.32) 0.450 0.87 (0.43–1.78) 0.71
 Lives alone 0.59 (0.31–1.11) 0.102 0.60 (0.25–1.46) 0.26
 Employed 0.69 (0.43–1.11) 0.123 0.58 (0.27–1.23) 0.16
Medical history
 History of stroke 0.76 (0.52–1.57) 0.719 0.73 (0.33–1.71) 0.50
 History of depression 4.54 (2.53–8.14)  < 0.001 4.11 (1.65–10.26) 0.002
 Prior SSRI use 3.60 (1.85–7.01)  < 0.001 1.51 (0.52–4.43) 0.45
Stroke admission
 NIHSS 1.05 (1.00–1.10) 0.032 1.05 (0.97–1.14) 0.21
 Inpatient PHQ-9 score 1.19 (1.11–1.28)  < 0.001 1.17 (1.06–1.30) 0.002
Stroke recovery
 Outpatient therapy 1.20 (0.69–2.12) 0.517 1.54 (0.71–3.36) 0.28

aAdjusted for age, sex, race, marital status, living situation, employment, history of stroke, history of depression, prior SSRI use, NIHSS, inpatient PHQ-9 score, and outpatient therapy