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. 2022 Nov 19;22:473. doi: 10.1186/s12876-022-02577-3

Table 2.

Clinicopathological features of main pancreatic duct (MPD)-involved type intraductal papillary mucinous neoplasms (IPMNs)

Total (n = 88) Low-intermediate grade (n = 47) High-grade/invasive carcinoma (n = 41) p
Age (years) 64.52 ± 8.83 64.94 ± 8.29 64.05 ± 9.48 0.641
Size (cm) 3.88 ± 1.94 3.95 ± 2.09 3.79 ± 1.75 0.702
Sex (male/female) 55/33 27/20 28/13 0.294
Location
 Head and neck 61 (69.32%) 28 (59.57%) 33 (80.49%) 0.046
 Body and tail 26 (30.68%) 18 (40.43%) 8 (19.51%)
CEA (ng/ml) 4.08 ± 4.46 3.24 ± 2.22 5.03 ± 5.99 0.060
CA19-9 (U/ml) 66.93 ± 299.17 16.04 ± 25.78 126.74 ± 435.65 0.085
MPD diameter (mm) 9.03 ± 4.33 8.15 ± 4.29 10.01 ± 4.22 0.045
Mural nodule (yes) 14 (15.91%) 4 (8.51%) 10 (24.39%) 0.042
Lymph node metastasis (yes) 2 (2.27%) 0 2 (4.88%) 0.214
Extra-pancreas extension (yes) 5 (5.68%) 0 5 (12.20%) 0.019
Symptom (yes) 38 (43.18%) 17 (36.17%) 21 (52.22%) 0.155
Pancreatitis (yes) 0 0 0
Diabetes Mellitus (yes) 17 (17.29%) 4 (8.51%) 13 (31.70%) 0.006
Complications (yes) 37 (42.05%) 20 (42.55%) 17 (41.46%) 0.918

CA19-9 carbohydrate antigen 19-9, CEA carcinoembryonic antigen