Table 3.
The clinical scores and exhaustion-related markers for predicting 90-day mortality
| Variables | ROC curve | Sensitivity (%) |
Specificity (%) | Youden index (%) | ||
|---|---|---|---|---|---|---|
| AUC (95% CI) | Best cutoff | p | ||||
| Lymphocytes | 0.688(0.535-0.842) | 8.75 | 0.023 | 64.40 | 76.50 | 40.90 |
| CD8+ T cell | 0.761(0.623-0.898) | 6.47 | 0.002 | 73.30 | 70.60 | 43.90 |
| PD-1 | 0.659(0.510-0.807) | 5.90 | 0.055 | 40.00 | 88.2 | 28.20 |
| Tim-3 | 0.745(0.615-0.875) | 16.55 | 0.003 | 68.90 | 70.60 | 39.50 |
| APACHE II Scores | 0.752(0.623-0.880) | 11.50 | 0.002 | 68.90 | 70.60 | 39.50 |
| SOFA Scores | 0.770(0.633-0.907) | 5.50 | 0.001 | 75.60 | 70.60 | 46.20 |
| LIPS Scores | 0.839(0.742-0.937) | 7.50 | 0.000 | 66.70 | 94.10 | 60.80 |
Abbreviations: PD-1, Programmed Cell Death 1; Tim-3, T-cell immunoglobulin mucin-3; APACHE, Acute Physiology and Chronic Evaluation; SOFA, Sequential Organ Failure Assessment; LIPS, Lung Injury Prediction Score; ROC, Receiver operating characteristics; AUC, area under the curve