Table 1.
Baseline patient, socio-demographic and clinical characteristics and geriatric assessment data
| Patients with data on falls at baseline available (n = 5759) | Patients with data on falls at follow-up available (n = 3681) | ||||
|---|---|---|---|---|---|
| Variable | Operationalization | N (%) | 95% CIa | N (%) | 95% CIa |
| Age (years) | 70–74 | 1212 (21.0) | 19.99–22.10 | 815 (22.1) | 20.80–23.48 |
| 75–79 | 1556 (27.0) | 25.87–28.17 | 1007 (27.4) | 25.92–28.80 | |
| 80–84 | 1668 (29.0) | 27.79–30.14 | 1038 (28.2) | 26.74–29.65 | |
| ≥85 | 1323 (23.0) | 21.87–24.04 | 821 (22.3) | 20.96–23.65 | |
| Median | 80.0 | 80.0 | |||
| Range | 70–101 | 70–100 | |||
| Sex | Male | 2626 (45.6) | 44.31–46.88 | 1601 (43.5) | 41.89–45.10 |
| Female | 3133 (54.4) | 53.12–55.69 | 2080 (56.5) | 54.90–58.11 | |
| Diagnosis general | Solid tumor/Carcinoma | 5218 (90.6) | 89.85–91.36 | 3352 (91.1) | 90.14–91.98 |
| Hematologic malignancy | 541 (9.4) | 8.64–10.15 | 329 (8.9) | 8.02–9.86 | |
| Diagnosis specific | New diagnosis | 4488 (77.9) | 76.86–79.00 | 2907 (79.0) | 77.66–80.29 |
| Relapse/ Progression | 1271 (22.1) | 21.00–23.14 | 774 (21.0) | 19.71–22.34 | |
| CCIa | Score 0 | 1486 (26.0) | 24.90–27.18 | 989 (27.0) | 25.58–28.46 |
| Score ≥ 1 | 4220 (74.0) | 72.82–75.10 | 2671 (73.0) | 71.54–74.42 | |
| Missing | 53 | 21 | |||
| Polypharmacya | Number 0–4 | 2052 (36.4) | 35.12–37.63 | 1355 (37.3) | 35.71–38.86 |
| Number ≥ 5 | 3589 (63.6) | 62.37–64.88 | 2279 (62.7) | 61.14–64.29 | |
| Missing | 118 | 47 | |||
| ECOG-PS | Score 0–1 | 2915 (50.6) | 49.32–51.91 | 2098 (57.0) | 55.40–58.60 |
| Score 2–4 | 2844 (49.4) | 49.32–51.91 | 1583 (43.0) | 41.40–44.60 | |
| Living situationa | Living alone | 2070 (36.0) | 34.70–37.18 | 1307 (35.5) | 33.96–37.05 |
| Living with others | 3179 (55.2) | 53.92–56.49 | 2080 (56.5) | 54.90–58.11 | |
| Other | 508 (8.8) | 8.12–9.59 | 294 (8.0) | 7.11–8.86 | |
| Missing | 2 | 0 | |||
| Professional home care a | No | 2694 (46.8) | 45.55–48.13 | 1696 (46.1) | 44.51–47.72 |
| Yes | 3057 (53.2) | 51.87–54.45 | 1982 (53.9) | 52.28–55.50 | |
| Missing | 8 | 3 | |||
| Geriatric domain | |||||
| FS: ADL (6–24) | Independent: score 6 | 2329 (40.5) | 39.1–41.7 | 1623 (44.1) | 42.5–45.7 |
| Dependent: score ≥ 7 | 3430 (59.5) | 58.0–61.0 | 2058 (55.9) | 54.0–58.0 | |
| FS: IADL a (0–5 (male)/8(female)) | Independent: score 8 (female) or 5 (male) | 1817 (31.8) | 30.3–32.7 | 1267 (34.4) | 33.0–36.0 |
| Dependent: score < 8 or 5 | 3902 (68.2) | 67.0–69.0 | 2401 (65.6) | 64.0–67.0 | |
| Missing | 40 | 13 | |||
| Pain (VAS) (0–10) a | No pain (score 0) | 2725 (48.3) | 47.0–49.6 | 1810 (50.1) | 48.4–51.7 |
| Mild pain (score 0.5–3) | 1086 (19.3) | 18.2–20.3 | 717 (19.8) | 18.5–21.1 | |
| Severe (score 3.5–10) | 1828 (32.4) | 31.2–33.6 | 1087 (30.1) | 28.6–31.6 | |
| Missing | 120 | 67 | |||
| Fatigue (VAS) (0–10) a | No fatigue (score 0) | 1261 (22.7) | 21.6–23.8 | 937 (26.3) | 24.8–27.7 |
| Presence of fatigue (score 0.5–10) | 4299 (77.3) | 76.0–78.0 | 2632 (73.5) | 72.0–75.0 | |
| Missing | 199 | 112 | |||
| Cognition (MMSE) (0–30) a | Score ≥ 24 = normal cognition | 3942 (76.9) | 75.7–78.1 | 2686 (80.1) | 78.8–81.5 |
| Score 18–23 = mild cognitive impairment | 831 (16.2) | 15.2–17.2 | 495 (14.8) | 13.6–16.0 | |
| Score ≤ 17 = severe cognitive impairment | 353 (6.9) | 6.2–7.6 | 170 (5.1) | 4.3–5.8 | |
| Missing | 633 | 330 | |||
| Depression (GDS) (0–15) a | Score 0–4 = not at risk for depression | 3301(62.8) | 61.5–64.1 | 2297 (66.8) | 65.3–68.4 |
| Score 5–15 = at risk for depression | 1954 (37.2) | 36.0–38.0 | 1140 (33.2) | 32.0–35.0 | |
| Missing | 504 | 244 | |||
| Nutrition (MNA-SF) (0–14) a | Normal nutritional status: score 12–14 | 1028 (17.9) | 16.9–18.9 | 760 (20.7) | 19.4–22.0 |
| Risk of malnutrition: score 8–11 | 2986 (52.0) | 50.7–53.3 | 2022 (55.1) | 53.4–56.6 | |
| Malnourished: score 0–7 | 1728 (30.1) | 28.9–31.3 | 891 (24.2) | 22.9–25.6 | |
| Missing | 17 | 8 | |||
aIn case of missings, calculation of the percentages and 95% CI were made by subtracting the missings from the denominator
Abbreviations: CCI Charlson Comorbidity Index, ECOG-PS Eastern Cooperative Oncology Group – Performance Status, FS functional status, ADL Activities of Daily Living, IADL Instrumental Activities of Daily Living, VAS Visual Analogue Scale, MMSE Mini Mental State Examination, GDS Geriatric Depression Scale, MNA-SF Mini Nutritional Assessment – Short Form