Table 5.

Crude and multivariable-adjusted ORs and 95% CIs for IBS subtypes across tertiles of dTAC

	Tertiles of dTAC			Ptrend
	T1 (< 6.06)	T2 (6.06–8.96)	T3 (> 8.96)
	OR	OR (95% CI)	OR (95% CI)
IBS-C
Crude	1.00	0.77 (0.56–1.06)	0.93 (0.68–1.26)	0.63
Model 1	1.00	0.75 (0.52–1.08)	0.99 (0.68–1.45)	0.99
Model 2	1.00	0.76 (0.52–1.09)	0.95 (0.64–1.40)	0.82
Model 3	1.00	0.73 (0.50–1.07)	0.92 (0.62–1.39)	0.71
Model 4	1.00	0.69 (0.46–1.01)	0.90 (0.60–1.37)	0.64
IBS-D
Crude	1.00	1.02 (0.69–1.51)	1.04 (0.70–1.54)	0.84
Model 1	1.00	1.24 (0.79–1.96)	1.39 (0.85–2.28)	0.19
Model 2	1.00	1.23 (0.78–1.96)	1.42 (0.86–2.33)	0.17
Model 3	1.00	1.35 (0.84–2.19)	1.52 (0.90–2.56)	0.12
Model 4	1.00	1.39 (0.86–2.25)	1.43 (0.84–2.43)	0.20
IBS-M
Crude	1.00	0.98 (0.64–1.48)	0.82 (0.53–1.27)	0.38
Model 1	1.00	0.95 (0.59–1.51)	0.89 (0.53–1.50)	0.66
Model 2	1.00	0.95 (0.59–1.52)	0.89 (0.52–1.51)	0.66
Model 3	1.00	1.16 (0.70–1.92)	1.08 (0.61–1.90)	0.80
Model 4	1.00	1.11 (0.67–1.85)	1.01 (0.57–1.79)	0.98
IBS-U
Crude	1.00	1.26 (0.90–1.76)	0.93 (0.65–1.34)	0.72
Model 1	1.00	1.56 (1.06–2.27)	1.21 (0.78–1.87)	0.42
Model 2	1.00	1.60 (1.09–2.34)	1.19 (0.76–1.85)	0.46
Model 3	1.00	1.53 (1.03–2.29)	1.07 (0.67–1.72)	0.78
Model 4	1.00	1.43 (0.95–2.15)	1.05 (0.65–1.70)	0.72

IBS-C: IBS with constipation; IBS-D: IBS with diarrhea; IBS-M: mixed IBS; IBS-U: unsubtyped IBS

Model 1: adjusted for age, gender, and energy intake

Model 2: further adjusted for physical activity, marital status, education level, smoking, chronic disease, medication use and dietary supplement intake

Model 3: further adjusted for regular meal pattern, eating rate, chewing sufficiency, breakfast skipping, fluid consumption, fried food intake, and dental status

Model 4: additionally, adjusted for BMI