Fig. 6.

TARID activated the ERK/MAPK signaling pathway through CXCL3. a Results of western blotting showing the expression of ERK and p-ERK in HTR8/SVneo cells transfected with vector-CXCL3 or vector and si-CXCL3 or si-NC. b Results of western blotting showing the expression of ERK and p-ERK in HTR8/SVneo cells transfected with vector-TARID or vector and ASO-TARID or ASO. c Results of western blotting showing the expression of CXCL3, ERK and p-ERK in HTR8/SVneo cells co-transfected with vector-TARID and si-CXCL3. d Results of western blotting showing the expression of CXCL3, ERK and p-ERK in HTR8/SVneo cells co-transfected with ASO-TARID and vector-CXCL3. All experiments were conducted in triplicate; the values are shown as the mean ± SEM; vs. vector or ASO，**P < 0.01, *P < 0.05; vs. vector-TARID + si-NC or ASO-TARID + vector, ##P < 0.01, #P < 0.05