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. 2022 Nov 18;17:90. doi: 10.1186/s13000-022-01272-x

Table 3.

Predictive values of synaptophysin immunohistochemistry in diagnosing classic Hodgkin lymphomas

Synaptophysin expression Classic Hodgkin lymphoma Non-
classic Hodgkin lymphoma*
Predictive values
Positive 11 0 PPV = 1
Negative 48 31 NPV = 0.392
Sensitivity = 0.186 Specificity = 1

*Non-classic Hodgkin lymphoma cases included diffuse large B-cell lymphoma, anaplastic large cell lymphoma, and extranodal marginal zone lymphoma of the mucosa-associated tissue

PPV positive predictive value, NPV negative predictive value