FIG. 5.

Complement-mediated lysis of 3.5-h schistosomula by serum antibodies elicited against recombinant 9B peptide-1-expressing flagella. Lysis of schistosomula in the presence of sera from normal C57BL/6J mice (bars A), sera from mice immunized i.n. with recombinant (bars B) or native (bars C) flagella, and sera from infected animals (positive control) (bars D) is shown. Guinea pig serum was used as a source of complement (■), and lysis was compared to that in the presence of heat-inactivated complement (□). Results are means and standard errors from three experiments.