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. Author manuscript; available in PMC: 2023 Oct 6.
Published in final edited form as: Annu Rev Cell Dev Biol. 2022 Jul 8;38:375–394. doi: 10.1146/annurev-cellbio-120320-033250

Figure 1.

Figure 1

Physical and physiological principles of fluid transport in epithelial tubes. (a) Schematic of basic parameters ruling fluid flux in epithelial tubes. The symbols cin/cout and Pin/Pout are the solute concentrations and pressures inside and outside the lumen, respectively. R is the lumen radius, and w is the width of the epithelial wall. (b–d) Basic parameters and laws ruling fluid flux. (e) Schematic of water and ion transport across an epithelial layer. Water may be transported via the paracellular or transcellular route. TJ stands for tight junction.