FIG. 1.

Time course of escape of Y. enterocolitica W22703c (biotype 2), A3064 (clinical, biotype 1A), T83 (clinical, biotype 1A), 61525 (clinical, biotype 1A), 937 (clinical, biotype 1A), AM5 (nonclinical, biotype 1A), IP2222 (nonclinical, biotype 1A), Eco88 (nonclinical, biotype 1A), and AM8 (nonclinical, biotype 1A) from HEp-2 epithelial cells. Bacteria were incubated with HEp-2 cells for 3 h and then exposed to 100 μg of gentamicin per ml for periods ranging from 1.5 to 16.5 h. At the end of this period, gentamicin-containing medium was replaced with fresh medium without gentamicin. After a further 3-h incubation, the medium was removed for enumeration of viable bacteria. Data are the mean of three independent experiments.