Central Illustration.

Study Flowchart and Forest Plots for the Adjusted HRs of Diabetes

From the pooled CREDO-Kyoto PCI/CABG (Coronary Revascularization Demonstrating Outcome Study in Kyoto Percutaneous Coronary Intervention/Coronary Artery Bypass Graft) registry, we found the excess risk of diabetes relative to nondiabetes for major adverse cardiovascular and cerebral endpoints MACCE was profound in the younger population, whereas no significant interaction was observed between adjusted risk of diabetes relative to nondiabetes for MACCE and other subgroups such as sex, mode of revascularization, and clinical presentation of acute myocardial infarction.