. 2022 Nov 12;2022:8901555. doi: 10.1155/2022/8901555

Table 5.

Packed cell volume of malaria-infected study mice treated with M. lanceolata methanol (80%) leaf extract in the four-day chemosuppressive study.

Test substances	Dose/day	Packed cell volume
Test substances	Dose/day	D0	D4	% change
PW	10 ml/kg	60.78 ± 2.04	41.80 ± 2.38	−30.68

ML	200 mg/kg	55.83 ± 2.73	40.73 ± 2.17	−25.82^b^∗∗
	400 mg/kg	61.45 ± 2.65	49.30 ± 2.33	−18.98^b^∗
	600 mg/kg	57.15 ± 2.94	50.65 ± 2.48	−10.56

CQ	25 mg/kg	58.42 ± 1.39	60.10 ± 1.09	2.97^a^∗∗∗

2% TW-80	10 ml/kg	46.50 ± 0.85	34.00 ± 1.44	−26.99

CF	200 mg/kg	50.83 ± 0.87	39.50 ± 1.52	−22.23^b^∗∗∗
	400 mg/kg	50.67 ± 1.36	44.33 ± 1.31	−12.40^a^∗∗^b^∗∗
	600 mg/kg	48.27 ± 1.76	40.25 ± 1.18	−16.21^a^∗^b^∗∗∗

CQ	25 mg/kg	59.64 ± 1.84	61.70 ± 1.79	3.51^a^∗∗∗

PW	10 ml/kg	53.12 ± 1.27	46.25 ± 1.41	−12.85

BF	200 mg/kg	51.82 ± 1.09	47.80 ± 1.40	−7.75^b^∗∗
	400 mg/kg	51.00 ± 0.97	47.60 ± 1.19	−6.66^b^∗∗
	600 mg/kg	52.00 ± 1.06	49.15 ± 0.96	−5.45^a^∗^b^∗∗

CQ	25 mg/kg	59.73 ± 0.99	61.96 ± 1.25	3.74^a^∗∗∗

PW	10 ml/kg	55.85 ± 1.37	49.75 ± 1.18	−10.58

DWF	200 mg/kg	57.94 ± 1.15	53.07 ± 1.25	−8.39^b^∗
	400 mg/kg	51.18 ± 1.28	47.19 ± 1.28	−7.71^b^∗
	600 mg/kg	53.52 ± 0.84	49.94 ± 1.22	−6.63^b^∗

CQ	25 mg/kg	60.82 ± 0.82	62.28 ± 0.79	2.41^a^∗∗

Values are designated as mean ± SEM (n = 6); ^a compared to PW, ^b to CQ 25 mg,: ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001; PW: pure water (negative control); ML: crude extract of M. lanceolata; 2% TW-80: 2% tween 80; CF: chloroform fraction; BF: n-butanol fraction; DWF: distilled water fraction; CQ: chloroquine; D0: values (pretreatment) on day 1; D4: values (posttreatment) on day 5.