Table 7.
Test substances | Dose/day | Packed cell volume | ||
---|---|---|---|---|
D3 | D7 | % change | ||
PW | 10 ml/kg | 44.50 ± 1.41 | 37.79 ± 1.32 | −15.08 |
| ||||
ML | 200 mg/kg | 46.17 ± 2.47 | 41.57 ± 1.35 | −9.45b∗ |
400 mg/kg | 54.50 ± 0.96 | 50.15 ± 1.28 | −7.98a∗ | |
600 mg/kg | 45.80 ± 1.47 | 43.80 ± 1.29 | −4.27a∗∗∗ | |
| ||||
CQ | 25 mg/kg | 47.62 ± 0.67 | 46.33 ± 0.85 | −2.72a∗∗∗ |
Values are designated as mean ± SEM (n = 6); a compared to PW, b to CQ 25 mg,: ∗P < 0.05, ∗∗∗P < 0.001; PW: pure water (negative control); ML: 80% methanol extract of M. lanceolata; CQ: chloroquine; D3: values (pretreatment) on day 4; D7: values (posttreatment) on day 8.