Table 8.

Weight (body) and temperature (rectal) of malaria-infected study mice treated with 80% methanol extract of M. lanceolata leaves in the chemoprophylactic test.

Test substances	Dose/day	Body weight (g)			Rectal temperature (°C)
		D4	D7	% change	D4	D7	% change
PW	10 ml/kg	29.70 ± 0.94	27.60 ± 1.05	−7.12	37.25 ± 0.21	35.30 ± 0.29	−5.22
ML	200 mg/kg	28.85 ± 0.97	27.68 ± 0.87	−4.00	36.75 ± 0.14	35.40 ± 0.34	−3.68b∗∗
	400 mg/kg	32.10 ± 0.64	31.13 ± 0.84	−3.04	37.32 ± 0.29	36.33 ± 0.29	−2.63a∗b∗
	600 mg/kg	30.05 ± 0.77	29.40 ± 0.79	−2.14a∗	36.57 ± 0.29	35.93 ± 0.22	−1.72a∗∗
CQ	25 mg/kg	30.73 ± 0.62	30.90 ± 0.36	0.66a∗∗	37.28 ± 0.15	37.25 ± 0.16	−0.09a∗∗∗

Values are designated as mean ± SEM (n = 6); ^a compared to PW, ^b to CQ 25 mg,: ^∗P < 0.05, ^∗∗P < 0.01, ^∗∗∗P < 0.001; PW: pure water (negative control); ML: 80% methanol extract of M. lanceolata; CQ: chloroquine. D4: preinfection values on day 5; D7: postinfection values on day 8.