Table 9.
Hematocrit of malaria-infected study mice treated with M. lanceolata methanolic (80%) leaf extract in the chemoprophylactic test.
| Test substances | Dose/day | Packed cell volume | ||
|---|---|---|---|---|
| D4 | D7 | % change | ||
| PW | 10 ml/kg | 50.10 ± 0.77 | 46.67 ± 1.17 | −6.86 |
|
| ||||
| ML | 200 mg/kg | 57.63 ± 1.04 | 54.73 ± 1.15 | −5.04b∗ |
| 400 mg/kg | 49.24 ± 1.20 | 47.20 ± 1.17 | −4.07 | |
| 600 mg/kg | 53.00 ± 0.82 | 51.50 ± 1.02 | −2.86 | |
|
| ||||
| CQ | 25 mg/kg | 47.91 ± 0.98 | 48.14 ± 1.32 | 0.41a∗∗ |
Values are designated as mean ± SEM (n = 6); a compared to PW, b to CQ 25 mg,: ∗P < 0.05, ∗∗P < 0.01; PW: pure water (negative control); ML: 80% methanol extract of M. lanceolata; CQ: chloroquine; D4: preinfection values on day 5; D7: postinfection values on day 8.