Table 1.
Unanimous prediction of deleterious missense SNPs in the ADAM33 protein by different online software.
| SNP ID | AAS | SIFT | PolyPhen-2 | PANTHER-PSEP | SNPs&GO | PROVEAN | GVGD | PredictSNP |
|---|---|---|---|---|---|---|---|---|
| rs773091023 | P678L | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs764301730 | C671R | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs751597707 | C669G | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs368984072 | G661R | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs777553708 | C637Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1334863089 | C631F | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs754867141 | C606S | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs754867141 | C606Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs915448220 | C573Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1432549895 | C519R | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1262246273 | Y513C | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1203116461 | P496L | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs757567846 | D483A | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1424975479 | C482F | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1165412077 | C482S | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs779669835 | R476C | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs748720838 | C475G | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs528261077 | G472V | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1378161696 | C463Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs768654352 | G460R | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1192357091 | C444S | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1192357091 | C444Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs777252478 | C439Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1321728445 | C431S | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs747255442 | G428C | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs776082098 | C420Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs751613984 | C388Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1313175203 | C371Y | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs764090883 | C371R | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1297854732 | C360R | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |
| rs1351880201 | D219V | Deleterious | Probably damaging | Probably damaging | Disease | Deleterious | C65 | Disease |