Table 1.
Clinical and pathological characteristics features of patients.
| Variables | NLNM | LNM | p value |
|---|---|---|---|
| 3409 (69.76%) | 1478 (30.24%) | ||
| Age at diagnosis | p < 0.001 | ||
| ≥65 | 1653 (48.49%) | 548 (37.08%) | |
| 50–65 | 1643 (48.20%) | 874 (59.13%) | |
| <50 | 113 (3.31%) | 56 (3.79%) | |
|
| |||
| Race | p=0.002 | ||
| White | 2764 (81.08%) | 1132 (76.59%) | |
| Black | 502 (14.73%) | 267 (18.06%) | |
| Other | 143 (4.19%) | 79 (5.35%) | |
|
| |||
| Sex | p=0.046 | ||
| Male | 2817 (82.63%) | 1186 (80.24%) | |
| Female | 592 (17.37%) | 292 (19.76%) | |
|
| |||
| Primary site | p < 0.001 | ||
| Supraglottis | 1027 (30.13%) | 824 (55.75%) | |
| Glottis | 1829 (53.65%) | 346 (23.41%) | |
| Subglottis | 128 (3.75%) | 36 (2.44%) | |
| Larynx | 238 (6.98%) | 152 (10.28%) | |
| Other | 187 (5.49%) | 120 (8.12%) | |
|
| |||
| Histology | p=0.522 | ||
| Squamous cell carcinoma | 3264 (95.75%) | 1421 (96.14%) | |
| Nonsquamous cell carcinoma | 145 (4.25%) | 57 (3.86%) | |
|
| |||
| Number of tumours | p=0.001 | ||
| 1 | 2081 (61.04%) | 1021 (69.08%) | |
| >1 | 1328 (38.96%) | 457 (30.92) | |
|
| |||
| Tumour size | p=0.001 | ||
| ≤3 cm | 2429 (71.25%) | 601 (40.66%) | |
| >3 cm | 980 (28.75%) | 877 (59.34%) | |
|
| |||
| Grade | p < 0.001 | ||
| Grade I | 575 (16.87%) | 63 (4.26%) | |
| Grade II | 2055 (60.28%) | 783 (52.98%) | |
| Grade III and IV | 779 (22.85%) | 632 (42.76%) | |
|
| |||
| T-stage | p < 0.001 | ||
| T1 | 1185 (34.76%) | 100 (6.77%) | |
| T2 | 589 (17.28%) | 229 (15.49%) | |
| T3 | 648 (19%) | 393 (26.59%) | |
| T4 | 987 (28.95%) | 756 (51.15%) | |
Notes: chi-square tests were compared between the two groups (p < 0.05 represents a statistically significant difference). Abbreviations: LNM, lymph node metastasis; NLNM, nonlymph node metastasis.