Table 2.
A univariate logistic regression analysis of variables related to LNM.
| Variables | OR | 95% CI | p value |
|---|---|---|---|
| Age at diagnosis | |||
| ≥65 | Reference | ||
| 50–65 | 1.495 | 1.070–2.089 | 0.019 |
| 50 | 1.605 | 1.414–1.821 | <0.001 |
|
| |||
| Race | |||
| White | Reference | ||
| Black | 1.299 | 1.102–1.530 | 0.002 |
| Other | 1.349 | 1.016–1.791 | 0.038 |
|
| |||
| Sex | |||
| Male | Reference | ||
| Female | 1.172 | 1.003–1.369 | 0.046 |
|
| |||
| Primary site | |||
| Supraglottis | Reference | ||
| Glottis | 0.236 | 0.204–0.273 | <0.001 |
| Subglottis | 0.351 | 0.239–0.513 | <0.001 |
| Larynx | 0.796 | 0.637–0.995 | 0.045 |
| Other | 0.80 | 0.625–1.024 | 0.076 |
|
| |||
| Histology | |||
| Squamous cell carcinoma | Reference | ||
| Nonsquamous cell carcinoma | 0.903 | 0.66–1.234 | 0.522 |
|
| |||
| Number of tumours | |||
| 1 | Reference | ||
| >1 | 0.701 | 0.616–0.799 | <0.001 |
|
| |||
| Tumour size | |||
| ≤3 cm | Reference | ||
| >3 cm | 3.617 | 3.184–4.109 | <0.001 |
|
| |||
| Grade | |||
| Grade I | Reference | ||
| Grade II | 3.478 | 2.647–4.568 | <0.001 |
| Grade III and IV | 7.405 | 5.594–9.802 | <0.001 |
|
| |||
| T-stage | |||
| T1 | Reference | ||
| T2 | 4.607 | 3.571–5.945 | <0.001 |
| T3 | 7.187 | 5.656–9.132 | <0.001 |
| T4 | 9.077 | 7.248–11.367 | <0.001 |
Notes: p < 0.05 represents a statistically significant difference. Abbreviations: LNM, lymph node metastasis.